The female Yautja are fearsome warriors just like their male brethren. Little is known about them and there are only a few notable specimens. When they have a mate, they prefer to hunt together, sometimes even die together. They are often more calculative than males, who tend to be more reckless. The female Yautja are usually bigger than males and some have feminine qualities, like breasts. The female Yautja have never been featured in the movies or games, they are only in the books and graphics novels. Here is a list of all notable female Yautja.
Sister Midnight was a female Yautja who found herself mysteriously drawn to the power of Witchlade. She breached the hull of a spacecraft that was attempting to infest Earth with Aliens. Sister Midnight fought a DarkAlien (a Xenomorph born from a Darkling) and was badly injured. She died while detonating her self-destruct device which destroyed the spaceship. However, she was able to complete her mission by destroying the Alien menace. Sister Midnight was featured in the Witchblade/Aliens/Darkness/Predator: Mindhunter crossover comic, released from 2000 to 2001.
Big Mama was a female elite hunter who had little female features but was much larger than an average Predator. Big Mama trained Caryn Delacroix (also known as Ash Parnall) and a group of mercenaries to be elite Alien hunters. Together they battle and killed several Aliens, white hybrids, robot Aliens and human soldiers. Although wounded several times, she is one of the few Predators to successfully survive the hunt. Big Mama was featured in the Aliens vs. Predator: Deadliest of the Species comic book, which is part of Aliens vs. Predator Omnibus: Volume 2.
Vagouti was a female Yautja who traveled to Earth together with her male companion, Nakande. Vagouti was larger and more experienced by Nakande, but they were both expert hunters or possible even retirees (wanting to make one last hunt). They wanted to exact revenge on humans who killed their brethren nine years before in Alaska. Together they located Sloane and Mary, two special forces snipers living a quiet life in a remote Oregon forest. Vagouti and Nakande slaughtered a group of bikers, but failed to kill Sloane and Mary. First Nakande was killed in an ambush. Sloane mortally wounded Vagouti, who set off her self-destruct device. However, the humans were able to escape the blast radius. Vagouti was a female Yautja in the Predator: If It Bleeds anthology book story "Rematch", released in 2017.
Machiko Noguchi was a human female who lived and hunted together with a Yautja clan for over a year. Although she was not a female Yautja per se, she was an accepted member of the group and went to several successful hunts with the Predators. She was blooded by Yautja elder Dachande on the colony planet Ryushi. Machiko Noguchi killed at least one Alien Queen and kept her head as a trophy on her wall. She used all the gear a normal Predator would but sometimes chose to use her trusty human pistol as well. Machiko Noguchi first debuted as the main character in the Aliens vs. Predator comic series, released from 1991. She had more adventures later in comics like Aliens vs. Predator: War and Aliens vs. Predator: Three World War.